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俞卫锋
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上海交通大学医学院附属仁济医院(三级甲等)
主任医师 | 麻醉科(疼痛科)
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医生简介俞卫锋,医学博士、主任医师、教授、博士研究生导师。现任上海交通大学医学院附属仁济医院麻醉科主任,上海交通大学医学院麻醉与危重病医学系主任。中国医师协会麻醉学医师分会第四届委员会会长,中华医学会麻醉学分会副主任委员,中华医学会麻醉学分会儿科学组组长,上海市医学会麻醉专科委员会第九届委员会主任委员,世界麻醉医师联盟(WFSA)疼痛委员会委员。并担任《麻醉·眼界》、《Anesthesiology》中文版主编,《中华麻醉学杂志》、《临床麻醉学杂志》、《JAPM》副总编辑。
主持9项并指导科室国家自然科学基金65项,以第一负责人承担25项省部级以上课题,主编专著11部。共发表论文300余篇,SCI收录100多篇,总IF>300分。有多篇发表在Anesthesiology、BJA、Pain、Stroke、Science Translation Medicine、 Nature Comunication等著名杂志上。获国家和军队科技进步二等奖各一项,另获总后勤部“科技新星”、上海市卫生系统“银蛇奖”、军队院校“育才奖”银奖、“上海市优秀学科带头人”、“上海市科技精英提名”等各种奖励、中国医师协会麻醉学分会(CAA)“中国杰出麻醉医师”、中华医学会麻醉学分会(CSA)“杰出研究奖”并入选国际华人麻醉学院(ICAA)“华人麻醉名人堂”等各种奖项。
以第一或通讯发表的SCI:(**为共同第一作者)
Yang LQ, Li SJ, Cao YF, Man XB, Yu WF*, Wang HY, Wu MC. Different alterations of cytochrome P450 3A4 isoform and its gene expression in livers of patients with chronic liver diseases. World J Gastroenterol. 2003 Feb;9(2):359-63.
Yang LQ, Yu WF**, Cao YF, Gong B, Chang Q, Yang GS. Potential inhibition of cytochrome P450 3A4 by propofol in human primary hepatocytes. World J Gastroenterol. 2003 Sep;9(9):1959-62.
Li Q, Yu WF**, Zhou MT, Lu X, Yang LQ, Zhu M, Song JG, Lu JH. Isoflurane preserves energy balance in isolated hepatocytes during in vitro anoxia/reoxygenation. World J Gastroenterol. 2005 Jul 7;11(25):3920-4.
Yu WF, Yang LQ, Zhou MT, Liu ZQ, Li Q. Ca2+ cytochemical changes of hepatotoxicity caused by halothane and sevoflurane in enzyme-induced hypoxic rats. World J Gastroenterol. 2005 Aug 28;11(32):5025-8.
Song JG, Cao YF, Yang LQ, Yu WF*, Li Q, Song JC, Fu XY, Fu Q. Awakening concentration of desflurane is decreased in patients with obstructive jaundice. Anesthesiology. 2005 Mar;102(3):562-5.
Song JC, Zhang MZ, Lu ZJ, Yang LQ, Song JG, Sun YM, Yu WF*. The effects of obstructive jaundice on the pharmacodynamics of propofol: does the sensitivity of intravenous anesthetics change among icteric patients? Acta Anaesthesiol Scand. 2009 Nov;53(10):1329-35.
Song JG, Cao YF, Sun YM, Ge YH, Xu XW, Yang LQ, Liu ZQ, Song SL, Yu WF*. Baroreflex sensitivity is impaired in patients with obstructive jaundice. Anesthesiology. 2009 Sep;111(3):561-5.
Xu XW, Pei SJ, Miao XR, Yu WF*. Human signal peptide had advantage over mouse in secretory expression. Histochem Cell Biol. 2009 Aug;132(2):239-46.
Li Z, Shi J, Liao Z, Wu FX, Yang LQ, Yu WF*. Scientific publications in anesthesiology journals from mainland China, Taiwan, and Hong Kong: a 10-year survey of the literature. Anesth Analg. 2010 Mar 1;110(3):918-21.
Song JC, Sun YM, Yang LQ, Zhang MZ, Lu ZJ, Yu WF*. A comparison of liver function after hepatectomy with inflow occlusion between sevoflurane and propofol anesthesia. Anesth Analg. 2010 Oct;111(4):1036-41.
Yang LQ, Song JC, Irwin MG, Song JG, Sun YM, Yu WF*. A clinical prospective comparison of anesthetics sensitivity and hemodynamic effect among patients with or without obstructive jaundice. Acta Anaesthesiol Scand. 2010 Aug;54(7):871-7.
Miao XR, Gao XF, Wu JX, Lu ZJ, Huang ZX, Li XQ, He C, Yu WF*. Bilateral downregulation of Nav1.8 in dorsal root ganglia of rats with bone cancer pain induced by inoculation with Walker 256 breast tumor cells. BMC Cancer. 2010 May 20;10:216.
Wu FX, Bian JJ, Miao XR, Huang SD, Xu XW, Gong DJ, Sun YM, Lu ZJ, Yu WF*. Intrathecal siRNA against Toll-like receptor 4 reduces nociception in a rat model of neuropathic pain. Int J Med Sci. 2010 Aug 2;7(5):251-9.
Yang LQ, Tao KM, Cheung CW, Liu YT, Tao Y, Wu FX, Yu WF*. The effect of isoflurane or propofol anaesthesia on liver injury after partial hepatectomy in cirrhotic patients. Anaesthesia. 2010 Nov 65(11):1094-1100.
Li Z, Liao Z, Wu FX, Yang LQ, Sun YM, Yu WF*. Scientific publications in critical care medicine journals from Chinese authors: a 10-year survey of the literature. J Trauma. 2010 Oct;69(4):E20-3.
Tao KM, Yang LQ, Liu YT, Tao Y, Song JC, Wu FX, Yu WF*. Volatile anesthetics might be more beneficial than propofol for postoperative liver function in cirrhotic patients receiving hepatectomy. Med Hypotheses. 2010 Dec;75(6):555-7.
Lu ZJ, Miao XR, Wu JX, Wang XY, Miao Q, Yu WF*. Acute PAR2 activation reduces alpha, beta-MeATP sensitive currents in rat dorsal root ganglion neurons. Neuroreport. 2010 Feb 17;21(3):227-32.
Yang T, Zhang J, Lu JH, Yang LQ, Yang GS, Wu MC, Yu WF*. A new staging system for resectable hepatocellular carcinoma: comparison with six existing staging systems in a large Chinese cohort. J Cancer Res Clin Oncol. 2011 May;137(5):739-50.
Li Z, Qiu LX, Wu FX, Yang LQ, Sun YM, Yu WF*. Scientific publications in anesthesiology journals from East Asia: a 10-year survey of the literature. J Anesth. 2011 Apr;25(2):257-62.
Song JC, Sun YM, Zhang MZ, Yang LQ, Tao TZ, Yu WF*. The etomidate requirement is decreased in patients with obstructive jaundice. Anesth Analg. 2011 Nov;113(5):1028-32.
Li Z, Qiu LX, Wu FX, Yang LQ, Sun S, Yu WF*. Scientific publications in international anaesthesiology journals: a 10-year survey. Anaesth Intensive Care. 2011 Mar;39(2):268-73.
Yang LQ, Tao KM, Liu YT, Cheung CW, Irwin MG, Wong GT, Lv H, Song JG, Wu FX, Yu WF*. Remifentanil preconditioning reduces hepatic ischemia-reperfusion injury in rats via inducible nitric oxide synthase expression. Anesthesiology. 2011 May;114(5):1036-47.
Ren HM, Yang LQ, Liu ZQ, Chen CY, Cheung CW, Tao KM, Song JG, Chen WR, Yu WF*. In vivo and ex vivo effects of propofol on myocardial performance in rats with obstructive jaundice. BMC Gastroenterol. 2011 Dec 28;11:144.
He Y, Wu FX, Miao XR, Xu XW, Sun YM, Chen CY, Yu WF*. Suppression of acute morphine withdrawal syndrome by adenovirus-mediated β-endorphin in rats. Brain Res. 2011 Nov 8;1422:13-9.
Huang Z, Tao K, Zhu H, Miao X, Wang Z, Yu W*, Lu Z. Acute PAR2 activation reduces GABAergic inhibition in the spinal dorsal horn. Brain Res. 2011 Nov 24;1425:20-6.
Wang Z, Sun Y, Wang Z, Wang Q, Yu W*. Anesthetic management of injuries following the 2008 Wenchuan, China earthquake. Eur J Trauma Emerg Surg (2011) 37:9–12.
Lv X, Wang ZM, Huang SD, Song SH, Wu FX, Yu WF*. Emulsified isoflurane preconditioning reduces lung injury induced by hepatic ischemia/reperfusion in rats. Int J Med Sci. 2011;8(5):353-61.
Wang Z, Bao Y, Lu Z, Yu W*. Is neuromuscular relaxation of rocuronium prolonged in patients with obstructive jaundice? Med Hypotheses. 2011 Jan;76(1):100-1.
Tao KM, Li XQ, Zhou QH, Moher D, Ling CQ, Yu WF*. From QUOROM to PRISMA: a survey of high-impact medical journals' instructions to authors and a review of systematic reviews in anesthesia literature. PLoS One. 2011;6(11):e27611.
Yang T, Zhang J, Lu JH, Yang GS, Wu MC, Yu WF*. Risk factors influencing postoperative outcomes of major hepatic resection of hepatocellular carcinoma for patients with underlying liver diseases. World J Surg. 2011 Sep;35(9):2073-82.
Wu JX, Xu MY, Miao XR, Lu ZJ, Yuan XM, Li XQ, Yu WF*. Functional up-regulation of P2X3 receptors in dorsal root ganglion in a rat model of bone cancer pain. Eur J Pain. 2012 Nov;16(10):1378-88.
Wu F, Xu X, Miao X, Chen J, Sun Y, Yu W*. Effect of recombinant adenovirus coding for endomorphin-2 on neuropathic pain in rats. Int J Clin Exp Pathol. 2012;5(9):914-23.
Wu F, Miao X, Chen J, Sun Y, Liu Z, Tao Y, Yu W*. Down-regulation of GAP-43 by inhibition of caspases-3 in a rat model of neuropathic pain. Int J Clin Exp Pathol. 2012;5(9):948-55.
Li Z, Wu FX, Yang LQ, Sun YM, Lu ZJ, Yu WF*. Citation classics in main pain research journals. J Anesth. 2012 Feb;26(1):85-93.
Wu F, Liu Y, Lv X, Miao X, Sun Y, Yu W*. Small interference RNA targeting TLR4 gene effectively attenuates pulmonary inflammation in a rat model. J Biomed Biotechnol. 2012;2012:406435.
Li Z, Qiu LX, Wu FX, Yang LQ, Sun YM, Lu ZJ, Yu WF*. Assessing the national productivity in subspecialty critical care medicine journals: a bibliometric analysis. J Crit Care. 2012 Dec;27(6):747.e1-5.
Song JC, Zhang MZ, Wu QC, Lu ZJ, Sun YM, Yang LQ, Yu WF*. Sevoflurane has no adverse effects on renal function in cirrhotic patients: a comparison with propofol. Acta Anaesthesiol Scand. 2013 Aug;57(7):896-902.
Wu F, Miao X, Chen J, Liu Z, Tao Y, Yu W*, Sun Y. Inhibition of GAP-43 by propentofylline in a rat model of neuropathic pain. Int J Clin Exp Pathol. 2013 Jul 15;6(8):1516-22.
Wang Z, Lv H, Song S, Shen X, Yang L, Yu W*. Emulsified isoflurane preconditioning protects isolated rat Kupffer cells against hypoxia/reoxygenation-induced injury. Int J Med Sci. 2013;10(3):286-91.
Lu YG, Wei W, Wang L, Tao KM, Sun YM, You ZD, Yu WF*. Ultrasound-guided cerebrospinal fluid collection from rats. J Neurosci Methods. 2013 May 15;215(2):218-23.
Wang ZM, Zhang P, Lin MJ, Tan B, Qiu HB, Yu WF*. Influence of obstructive jaundice on pharmacodynamics of rocuronium. PLoS One. 2013 Oct 16;8(10):e78052.
Li Z, Sun YM, Wu FX, Yang LQ, Lu ZJ, Yu WF*. Equal contributions and credit: an emerging trend in the characterization of authorship in major anaesthesia journals during a 10-yr period. PLoS One. 2013 Aug 5;8(8):e71430.
Chen Q, Chen P, Zhou S, Yan X, Zhang J, Sun X, Yuan H, Yu W*. Hydrogen-rich saline attenuated neuropathic pain by reducing oxidative stress. Can J Neurol Sci. 2013 Nov;40(6):857-63.
Ge Y, Wu F, Sun X, Xiang Z, Yang L, Huang S, Lu Z, Sun Y, Yu WF*. Intrathecal Infusion of Hydrogen-Rich Normal Saline Attenuates Neuropathic Pain via Inhibition of Activation of Spinal Astrocytes and Microglia in Rats. PLoS One. 2014 May 23;9(5):e97436.
Li Z, Sun YM, Wu FX, Yang LQ, Lu ZJ, Yu WF*. Controlled low central venous pressure reduces blood loss and transfusion requirements in hepatectomy. World J Gastroenterol. 2014 Jan 7;20(1):303-9.
Tao KM, Tao Y, Chen CY, Yang LQ, Lu ZJ, Sun YM, Huang SD, Yu WF*. Proteinase-activated Receptor 1 Contributed to Up-regulation of Enkephalin in Keratinocytes of Patients with Obstructive Jaundice. Anesthesiology. 2014 Jul;121(1):127-39 .
Huang ZX, Lu ZJ, Ma WQ, Wu FX, Zhang YQ, Yu WF*, Zhao ZQ. Involvement of RVM-expressed P2X7 receptor in bone cancer pain: mechanism of descending facilitation. Pain. 2014 Apr;155(4):783-91.
Zhang C, Wang Z, Zhang J, Qiu H, Sun Y, Yang L, Wu F, Zheng J, Yu W*. Competitive inhibition of the nondepolarizing muscle relaxant rocuronium on nicotinic acetylcholine receptor channels in the rat superior cervical Ganglia. J Cardiovasc Pharmacol. 2014 May;63(5):428-33.
Liu Y, Yang L, Tao K, Vizcaychipi MP, Lloyd DM, Sun X, Irwin MG, Ma D, Yu W*. Protective effects of hydrogen enriched saline on liver ischemia reperfusion injury by reducing oxidative stress and HMGB1 release. BMC Gastroenterol. 2014 Jan 12;14:12.
Zhang C, Wang Z, Dong J, Pan R, Qiu H, Zhang J, Zhang P, Zheng J, Yu W*. Bilirubin modulates acetylcholine receptors in rat superior cervical ganglionic neurons in a bidirectional manner. Sci Rep. 2014 Dec 15;4:7475.
Feixiang Wu, Ruirui Pan, Jiaying Chen, Megumi Sugita, Caiyang Chen, Yong Tao, Weifeng Yu*, Yuming Sun. Lentivirus mediated siRNA against GluN2B subunit of NMDA receptor reduces nociception in a rat model of neuropathic pain. Biomed Res Int. 2014;2014:871637.
Song JC, Lu ZJ, Jiao YF, Yang B, Gao H, Zhang J, Yu WF*.Etomidate Anesthesia during ERCP Caused More Stable Haemodynamic Responses Compared with Propofol: ARandomized Clinical Trial. Int J Med Sci.2015, Jul 3;12(7):559-65.
Pan R, Di H, Zhang J, Huang Z, Sun Y, Yu W*, Wu F*. Inducible Lentivirus-Mediated siRNA against TLR4 Reduces Nociception in a Rat Model of Bone Cancer Pain. Mediators Inflamm. 2015;2015:523896.
Zhao J, Yu W**,Tong C, Xie Z, Sun J, Zhou SF, Liu H, Meng L. Adopting the American anesthesia oral examination in China: value and roadblocks. J Clin Anesth. 2016 May;30:42-5.
Yuan YW, Wang L, Lu ZY, Long Y, Jiao YF, Xia Q, Wen DX, Yu WF*. Overexcited MaxiK and KATP channels underlie obstructive jaundice-induced vasoconstrictor hyporeactivity of arterial smooth muscle.Scientific Reports.2016,6: 39246.
Li PY, Wang X, Stetler RA, Chen J, Yu WF*. Anti-inflammatory signaling: the point of convergence for medical gases in neuroprotection against ischemic stroke. Med Gas Res. 2016 Dec 30;6(4):227-231.
Wu FX, He Y, Di HT, Sun YM, Pan RR, Yu WF*, Liu R*. An Engineered Endomorphin-2 Gene for Morphine Withdrawal Syndrome. PLoS One. 2016 Mar 22;11(3):e0149877.
Dong R, Yu B, Chen L, Yu W*.The 5-HT2A receptor potassium-chloride cotransporter 2 signaling pathway in a rat incision pain model.Exp Ther Med. 2016 Dec;12(6):3583-3588.
Rongrong Ren, Yanfei Mao, Zhengshang Ruan, Yan Wang, Yan Zhang, Junming Du, Weifeng Yu*. Celastrol attenuates ventilator induced lung injury in mouse through inhibition of MAPK pathway. Int J Clin Exp Pathol 2017;10(9): 9302-9309.
Wang Long, Zhou Mai-Tao, Chen Cai-Yang, Yin Wen, Wen Da-Xiang*, Cheung Chi-Wai, Yang Li-Qun, Yu Wei-Feng*. Increased Renal Clearance of Rocuronium Compensates for Chronic Loss of Bile Excretion, via upregulation of Oatp2. Sci Rep. 2017, 7:40438.
Wang Li-Qin, Xu Hui-Hong, Ge Yan-Hu, Zhu Hai, Yu Da-Wei, Yu Wei-Feng*, Lu Zhi-Jie*. Establishment of a murine pancreatic cancer pain model and microarray analysis of pain‑associated genes in the spinal cord dorsal horn. Mol Med Rep. 2017, 16(4):4429-4436.
Er-liang Kong, Xiao- Zhi Wu, Yan He, Hong-qian Wang, Yan Zhang, Jin-min Zhang, Wei-feng Yu*, FeixiangWu*.TLR4 inhibits spinal gabaergic activities via microglial activation in chronic constriction injury mice.Neuropsychiatry (London). 2018 ,8(2): 761–771.
Ge Yan-Hu, Jiao Ying-Fu, Li Pei-Ying, Xiang Zheng-Hua, li Zhi, Wang Long, Li Wen-Qian, Gao Hao, Shao Jia-Yun, Wen Da-Xiang, Yu Wei-Feng*. Coregulation of endoplasmic reticulum stress and oxidativestress in neuropathic pain and disinhibition of the spinal nociceptive circuitry. Pain. 2018, 159(5):894-906.
Li Y, Zhu ZY, Huang TT, Zhou YX, Wang X, Yang LQ, Chen ZA, Yu WF*, Li PY*.The peripheral immune response after stroke-A double edge sword for blood-brain barrierintegrity. CNS Neurosci Ther. 2018 Dec;24(12):1115-1128.
Wang L, Zhou Y, Yin J, Gan Y, Wang X, Wen D, Thomson A W, Hu X, Yang L, Stetler R A, Li P*, Yu W*. Cancer Exacerbates Ischemic Brain Injury Via Nrp1 (Neuropilin 1)-Mediated Accumulation of Regulatory T Cells Within the Tumor [J]. Stroke, 2018, 49(11): 2733-42.
Wang X, Xuan W, Zhu ZY, Li Y, Zhu H, Zhu L, Fu DY, Yang LQ, Li PY*, Yu WF*. The evolving role of neuro-immune interaction in brain repair after cerebral ischemic stroke. CNS Neurosci Ther. 2018 Dec;24(12):1100-1114.
Luo T, Yu S, Cai S, Zhang Y, Jiao Y, Yu T*, Yu W*. Parabrachial Neurons Promote Behavior and Electroencephalographic Arousal From GeneralAnesthesia. Front Mol Neurosci. 2018 Dec 4;11:420.
Gu H, Deng X, Lv Y, Chen Q, Yu W*.Preoperational chronic pain impairs the attention ability before surgery and recovery of attention and memory abilities after surgery in non-elderly patients. J Pain Res. 2018 Dec 27;12:151-158
Luo P, Shao J, Jiao Y, Yu W*, Rong W*. CC chemokine ligand 2 (CCL2) enhances TTX-sensitive sodium channel activity of primary afferent neurons in the complete Freud adjuvant-induced inflammatory pain model. Acta Biochim Biophys Sin (Shanghai). 2018 Dec 1;50(12):1219-1226.
Xie K, Zhang W, Fang J, Guo Y, Fang M, Ding Z, Hu Y, Yu W*, Li F. Prevalence and risk factors of atrial fibrillation during lung and esophageal surgery: A Prospective observational study. Medicine (Baltimore). 2018 Jul;97(30):e11549.
Wu Fei-Xiang, Babazada Hasan, Gao Hao, Huang Xi-Ping, Xi Chun-Hua, Chen Chun-hua,MD, Xi Jin, Yu Wei-Feng*, Liu Ren-Yu*. Dezocine Alleviates Morphine-Induced Dependence in Rats. Anesth Analg. 2019 Jun;128(6):1328-1335.
Kong EL, Zhang JM, An N, Tao Y, Yu WF*, Wu FX*. Spironolactone rescues renal dysfunction in obstructive jaundice rats by upregulating ACE2 expression. J Cell Commun Signal. 2019 Mar;13(1):17-26.
Wang HQ, Meng XY, Chen M, Xu SH, Zhu M, Lu X, Wu FX*, Yu WF*. Bile acids elicited endothelium-dependent vasoconstrictor hypo-activity through TRPV4 channels in the thoracic aorta of bile duct ligation rats. Biomed Pharmacother. 2019 Jan;109:511-518.
Wang X, Zhou Y, Tang D, Zhu Z, Li Y, Huang T, Müller R, Yu W*, Li P*. ACC1 (Acetyl Coenzyme A Carboxylase 1) Is a Potential Immune Modulatory Target of Cerebral Ischemic Stroke. Stroke. 2019 Jul;50(7):1869-1878
Li Q, Lu J, Zhou X, Chen X, Su D, Gu X*, Yu W*. High-Voltage-Activated Calcium Channel in the Afferent Pain Pathway: An Important Target of Pain Therapies. Neurosci Bull. 2019 Dec;35(6):1073-1084.
Wang X, Liu Y, Wu X, Zhang Y, Pan R, Yu W*, Wu F*. Engineered endomorphin-2 gene: A novel therapy for improving morphine reinstatement in CPP model of rats by using deficient adenovirus as the vector. Biochem Biophys Res Commun. 2019 May 21;513(1):141-146.
He Y, Lu Y, Shen Y, Wu F, Xu X, Kong E, Huang Z, Sun Y*, Yu W*. Transgenic increase in the β-endorphin concentration in cerebrospinal fluid alleviates morphine-primed relapse behavior through the μ opioid receptor in rats. J Med Virol. 2019 Jun;91(6):1158-1167.
Huang D, Chen M, Wang Z, Hou L, Yu W*.Electroacupuncture Pretreatment Attenuates Inflammatory Lung Injury After Cardiopulmonary Bypass by Suppressing NLRP3 Inflammasome Activation in Rats. Inflammation. 2019 Jun;42(3):895-903.
Hao Gao, Xiao-Yan Meng, Hong-Qian Wang, Feng-Feng Zhu, Er-Liang Kong, Sai-Hong Xu, Mei Zhu, Ai-Ling Guo, Ting Yu, Jin-Chao Song*, Wei-Feng Yu*. Association between Anaesthetic Technique and Oncological Outcomes after Colorectal Carcinoma Liver Metastasis Resection . International journal of medical sciences, 2019, 16(2): 337-42.
Sihan Chen , Xian-Yu Liu , Yingfu Jiao , Zhou-Feng Chen *, Weifeng Yu*.NPY2R signaling gates spontaneous and mechanical, but not thermal, pain transmission, Mol Pain, 2019;15:1-7.
Yuxuan Lin , Xiaoqing Zhang , Lizhi Li* , Mengyun Wei , Bin Zhao , Xiaojing Wang , Zhiying Pan , Jie Tian* , Weifeng Yu *, Diansan Su*. High-flow nasal cannula oxygen therapy and hypoxia during gastroscopy with propofol sedation: a randomized multicenter clinical trial.Gastrointest Endosc, 2019;90(4):591-601.
Ling Zhu , Xiao Shi , Suqing Yin , Jiemin Yin , Ziyu Zhu , Xiong Gao , Yingfu Jiao , Weifeng Yu* , Liqun Yang*. Effectiveness and pulmonary complications of perioperative laryngeal mask airway used in elderly patients (POLMA-EP trial): study protocol for a randomized controlled trial.Trials, 2019 May 8;20(1):260. IF=1.975
Ziyu Zhu , Li Zheng , Yan Li , Tingting Huang , Yu-Chieh Chao , Lijun Pan , Hui Zhu , Yanhua Zhao , Weifeng Yu *, Peiying Li*.Potential Immunotherapeutic Targets on Myeloid Cells for Neurovascular Repair After Ischemic Stroke. Front Neurosci, 2019 Aug 9;13:758. (Review)
Gu H, Deng X, Lv Y, Chen Q, Yu W*.Preoperational chronic pain impairs the attention ability before surgery and recovery of attention and memory abilities after surgery in non-elderly patients. J Pain Res. 2019, 12:151-158
Yu-gang Lu, Long Wang, Jiang-long Chen,Jiao Zhu, Xiao-yan Meng, Zhen-dong You,Wei-feng Yu*. Projections from lateral habenular to tail of ventral tegmental area contribute to inhibitory effect of stress on morphine-induced conditioned place preference. Brain Research , 2019 Aug 15;1717:35-43.
Yan Li , Zi-Yu Zhu , Bing-Wei Lu , Ting-Ting Huang , Yue-Man Zhang , Na-Ying Zhou , Wei Xuan , Zeng-Ai Chen , Da-Xiang Wen , Wei-Feng Yu *, Pei-Ying Li*. Rosiglitazone ameliorates tissue plasminogen activator‐induced brain hemorrhage after stroke. CNS Neurosci Ther. 2019 ,25(12):1343-1352.
Qi Li , Zi-Yu Zhu , Jian Lu , Yu-Chieh Chao , Xiao-Xin Zhou , Ying Huang , Xue-Mei Chen , Dian-San Su , Wei-Feng Yu *, Xi-Yao Gu*. Sleep deprivation of rats increases postsurgical expression and activity of L-type calcium channel in the dorsal root ganglion and slows recovery from postsurgical pain, Acta Neuropathol Commun. 2019 Dec 23;7(1):217.
Dongxiao Huang , Mo Chen , Zhankui Wang , Lei Hou , Weifeng Yu*. Electroacupuncture Pretreatment Attenuates Inflammatory Lung Injury After Cardiopulmonary Bypass by Suppressing NLRP3 Inflammasome Activation in Rats. Inflammation, 2019 Jun;42(3):895-903.
Dan Tang , Yi Chen , Gong-Bo Fu , Tian-Jie Yuan , Wei-Jian Huang , Zhen-Yu Wang , Wei-Jian Li , Ying-Fu Jiao* , Wei-Feng Yu* , He-Xin Yan*. EpCAM inhibits differentiation of human liver progenitor cells into hepatocytes in vitro by activating Notch1 signaling, Biochem Biophys Res Commun, 2020, 525(1):238-243.
Yi Chen , Dan Tang , Linjie Zhu , Tianjie Yuan , Yingfu Jiao , Hexin Yan , Weifeng Yu *. hnRNPA2/B1 Ameliorates LPS-Induced Endothelial Injury through NF- κ B Pathway and VE-Cadherin/ β-Catenin Signaling Modulation In Vitro, Mediators Inflamm. 2020 May 30;2020:6458791.
Xiaoqiang Wang , Weiying Xie , Shuyuan Gan , Tao Wang , Xuexin Chen , Diansan Su , Jiaxin Sun , Jiapiao Lin , Feixiang Wu , Pingbo Xu , Changhong Miao , Min Yan , Shengmei Zhu , Bo Zhai , Yuming Sun* , Weifeng Yu* , Jie Tian#. Effects of general anesthesia versus local anesthesia in primary hepatocellular carcinoma patients presenting for thermal ablation surgery: a multiple center retrospective cohort study with propensity score matching , Annals of Translational Medicine, 2020;8(6):277.
Tingting Huang , Yan Li , Yuxi Zhou , Bingwei Lu , Yueman Zhang , Dan Tang , Yu Gan , Zhengzhou He , Zengai Chen , Weifeng Yu* , Peiying Li* . Stroke Exacerbates Cancer Progression by Upregulating LCN2 in PMN-MDSC, Front Immunol, 2020 Feb 21;11:299.
Jiru Zhang , Gang Liu , Dandan Chen , Zhiqiang Wang , Dan Chen , Youwei Liu , Weifeng Yu* . The combination of CC chemokine receptor type 5(CCR5) and Treg cells predicts prognosis in patients with ischemic stroke, J Neuroimmunol. 2020 Dec 15;349:577404.
Shaoxia Duan, Yingfu Jiao , Jiemin Wang , Dan Tang , Saihong Xu , Ruoxi Wang , Tao Jiang , Jianlin Shao , Zhenzhou He *, Weifeng Yu *. Impaired B-Cell Maturation Contributes to Reduced B Cell Numbers and Poor Prognosis in Sepsis , Shock ,2020 Jul;54(1):70-77.
Rongrong Ren, Zhengshang Ruan, Haoshu Ding, Junming Du, Weifeng Yu*. Phosphoproteome Profiling Provides Insight into the Mechanisms of Ventilator-induced Lung Injury. Exp Ther Med. 2020 Jun;19(6):3627-3633.
Li WJ, Zhu XJ, Yuan TJ, Wang ZY, Bian ZQ, Jing HS, Shi X, Chen CY, Fu GB, Huang WJ, Shi YP, Liu Q, Zeng M, Zhang HD, Wu HP, Yu WF*, Zhai B*, Yan HX*. An extracorporeal bioartificial liver embedded with 3D-layered human liver progenitor-like cells relieves acute liver failure in pigs, Sci Transl Med, 2020 Jul 8;12(551):eaba5146.
Cheng Lv , Xiyao Gu , Haowen Li , Yumeng Zhao , Donglei Yang , Weifeng Yu *, Da Han* , Juan Li , Weihong Tan*. Molecular Transport through a Biomimetic DNA Channel on Live Cell Membranes, ACS Nano. 2020 Nov 24;14(11):14616-14626.
主编著作
1. 曹云飞,俞卫锋,王士雷主编.全麻原理及研究新进展.人民军医出版社2005年
2. 杭燕南,俞卫锋,王祥瑞主编.吸入麻醉药.世界图书出版公司2008年3月
3. 俞卫锋主编. 麻醉与复苏新论. 第二军医大学出版社 2001年6月
4. 李保春,俞卫锋,袁伟杰主编.多器官功能衰竭.人民军医出版社 2004年2月
5. 陆智杰,俞卫锋主编. 内脏痛-基础与临床.人民军医出版社 2013年8月
6. 闻大翔,欧阳葆怡,俞卫锋主编.当代麻醉药理学丛书:肌肉松弛药,世界图书出版公司2015.6第2版
7. 杭燕南,俞卫锋,于布为,王祥瑞主编. 当代麻醉手册. 世界图书出版公司2016.3第3版
8. 俞卫锋主编,杭燕南审阅. 肝胆手术麻醉和围术期处理. 世界图书出版公司2016.8第1版
9. 俞卫锋,石学银,姚尚龙主编. 临床麻醉学理论与实践. 人民卫生出版社2017.4第1版
10. 俞卫锋,缪长虹,董海龙,袁红斌主编. 麻醉与围术期医学. 世界图书出版公司2018.11第1版
11. 王祥瑞,张晓庆,俞卫锋,顾卫东主译. 麻醉科5分钟速查. 上海科学技术出版社2018.6第1版
12. 童传耀,俞卫锋主编. 麻醉医师面试病例集锦. 世界图书出版公司2018.10第1版
13. 范颖晖,俞卫锋主译. 疼痛医学基础. 世界图书出版公司 2020.10第1版
课题研究
1、卤代类吸入麻醉药的肝毒性研究,国家自然科学基金(39170713),1991.1-1994.12
2、吸入麻醉药肝毒性与肝线粒体功能及膜分子机制的研究,国家自然科学基金(39400126),1994.1-1997.12
3、阻塞性黄疸导致吸入全麻药敏感性增高的突触传递机制研究,国家自然科学基金(81072625),2011.1-2013.12
4、活性氧作用于α肾上腺受体致阻塞性黄疸血管低反应性,国家自然科学基金(81170427),2012.1-2015.12
5、miR-150调控内皮祖细胞修复血管内皮介导阻黄血管低反应,国家自然科学基金(81370513),2014.1-2017.12
6、肝移植中异丙酚药代动力学研究,军队医药基金项目(98Q50),1998-2001
7、上海市临床医学中心,上海市专项基金(ZX01B05),2001-2002
8、肝脏手术围术期肝功能保护策略研究,上海市科委生物医药重点项目(10411952000),2011-2013,
9、阻塞性黄疸导致吸入全麻药敏感性增高的突触传递机制研究,上海市教育委员会科研创新项目/重点项目,2011-2013,15万
10、阻塞性黄疸导致吸入全麻药敏感性增高的突触传递机制研究,上海市科委优秀学科带头人计划(11XD1406800),2012-2015,40万
11、术前疼痛易化术后认知功能障碍发生的中脑五羟色胺调控机制,国家自然科学基金(81571048),2016.1-2019.12,67万
12、上海市卫生计生系统重要薄弱学科建设(2015ZB0101),组长单位, 2016.1-2018.12,200万
13、术前疼痛易化术后认知功能障碍发生的多中心临床研究,浦东新区卫生和计划生育委员会联合攻关项目(PW2015D-3), 2015.11-2017.10,20万
14、十三五国家重点研发计划课题,2018YFA0108204,功能细胞的获取及评价和相关技术标准的建立,2018/07- 2022/12 月,780万
15、Tmem 100蛋白调节TRPV1/A1通道复合体功能平衡—围术期外周痛/痒感觉编码的新见解(2019-01-07-00-01-E00074),上海市教育委员会科研创新计划自然科学重大项目,2019.1-2023.12,300万
16、老年患者围术期喉罩应用与肺部并发症的多中心、随机对照临床研究(SHDC12016102),2016.9-2019.9,180万
17、浦东新区卫生和计划生育委员会 学科建设,2017.10-2021.9,120万
18、可弯曲纤维支气管镜诊疗复合镇静方案的多中心随机对照临床研究(16411950300),2016.7-2019.9,90万
19、CD8+T细胞活化与脑浸润加重围术期脑卒中后神经轴突脱髓鞘的肠脑互动,国自然面上(81971223),2020.1.1-2023.12.31,55万元
20、限制饮食通过嘌呤代谢途径维持CD4+T细胞线粒体稳态减少卒中后免疫抑制(M-0351),国家自然科学基金委员会中德科学中心2020年度中德合作交流项目,2021.1.1-2023.12.31,俞卫锋,RMB150万
21、“脊髓—延髓”间门控疼痛的新环路机制(32030043),NSFC-重点项目,2021.1.1-2025.12.31,俞卫锋,292万
创新专利
1.俞卫锋,徐学武.一种获得内吗啡肽的方法及其在疼痛治疗中的应用(200510118974.0)
2.俞卫锋,徐学武.可基因整合的重组腺相关病毒载体的构建方法.(200510118975.5)
3.俞卫锋,吴飞翔. 一种用于戒毒的生物新方法 (香港国际发明博览会金奖)
4. 俞卫锋,吴飞翔. 一种人鼠同源性NMDA受体NR2B的小RNA及其应用(907676 ,ZL2010 1 0247740.7)
5. 吴飞翔,俞卫锋,张金旻.一种干扰TLR4受体的小RNA及其应用(ZL2014 1 0043633.0)
6. 俞卫锋,俞卫中,俞文锴 可智能镇痛的输注泵监控系统及方法(ZL 2014 1 0156960.7)
7. 郑蓓洁,俞卫锋,陈杰,王青.一种用于穴位艾灸的便携式手持器(ZL201922058252.0)
8. 郑蓓洁,俞卫锋,陈雪青,周佳青.一种改良的用于刺血的负压抽气式AS罐(ZL201922059890.4)
获得荣誉
1. 吸入麻醉药的研究 2004年国家科技进步二等奖 (第二)
2. 吸入麻醉药肝毒性机制的研究 2002 年军队科技进步二等奖 (第一)
3. 肝胆疾患围术期血液内环境紊乱机制 2006年军队科技进步三等奖(第二)
4. 2007年军队院校育才奖 银奖
5. 2006年上海市卫生系统“银蛇奖” 银奖
6. 2005年上海市优秀医学青年人才计划 (固定带教老师)
7. 2006年上海市科技启明星 (指导老师)
8. 2008年上海市科技启明星 (指导老师)
9. 2011年上海市优秀学科带头人
10. 2011年军队二类津贴
11. 2011 年上海市优秀博士论文 (导师 俞卫锋 )
12. 2013年上海市科技精英提名奖
13.2017年中国医师协会麻醉学分会(CAA)“中国杰出麻醉医师”
14.2017年中华医学会麻醉学分会(CSA)“中国杰出研究奖”
15.2020年“提高肝病患者围术期救治质量的保障体系建立与关键技术”高等学校科学研究优秀成果奖(科学技术)一等奖2020-194(第一完成人) -
执业点上海交通大学医学院附属仁济医院(三级甲等)麻醉科(疼痛科)