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廖建友
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中山大学孙逸仙纪念医院(三级甲等)
基础与转化医学研究中心
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医生简介廖建友,博士,副研究员,博士生导师。现任生物信息中心主任,医研中心党支部书记。入选人才计划:广东省杰出青年科学基金、广东省“特支计划”科技创新青年拔尖人才、广州市“珠江科技新星”人才培养计划、孙逸仙纪念医院“逸仙优秀青年医学人才”培养计划。从事RNA生物学、肿瘤学、大数据分析等多学科交叉研究,拥有一个干湿结合的混合研究团队。到目前为止以第一或者通讯作者的身份发表SCI收录论文12篇,包括Cell(IF:36.216),PNAS(IF:9.674),Genome Biology(IF:14.028,封面文章),Nucleic Acids Research(IF:11.147)等高水平专业杂志,以共同作者身份在国际顶级杂志Cell(IF:36.216)、Nature Biotechnology(IF:41.514)等发表13篇研究论文。本人研究受到了8项省部级以上RNA相关基金资助,包括4项国家自然科学基金。目前主要兴趣点在利用RNA生物学结合大数据技术系统阐述RNA蛋白互作网络促进乳腺癌发生发展的功能和机制。
联系方式:liaojy3@mail.sysu.edu.cn
发表论文:
- Y Lu*, Q Zhao*, J. Y. Liao*(共同第一), E Song, Q Xia, J Pan, Y Li, J Li, B Zhou, Y Ye, C Di, S Yu, Y Zeng, S Su # Complement Signals Determine Opposite Effects of B Cells in Chemotherapy-Induced Immunity, Cell (2020), 180, 1–17(IF:36.216)
- J. Y., Liao, *# (共同通讯), B., Yang*,Y. C., Zhang*, D. C., Lin#, D., Yin#, EuRBPDB: a comprehensive resource for annotation, functional and oncological investigation of eukaryotic RNA binding proteins (RBPs). Nucleic Acids Res (2019) , gkz823. (IF:11.147)
- J. Y., Liao, Y. H. Guo, L. L. Zheng, Y. Li, W. L. Xu, Y. C. Zhang, H. Zhou, Z. R. Lun, F. J. Ayala and L. H. Qu (2014). "Both endo-siRNAs and tRNA-derived small RNAs are involved in the differentiation of primitive eukaryote Giardia lamblia." Proc Natl Acad Sci U S A 111(39): 14159-14164.(IF:9.674)
- Zhang, Y. C.*, J. Y., Liao*(共同第一), Z. Y. Li, Y. Yu, J. P. Zhang, Q. F. Li, L. H. Qu, W. S. Shu and Y. Q. Chen (2014). "Genome-wide screening and functional analysis identify a large number of long noncoding RNAs involved in the sexual reproduction of rice." Genome Biol 15(12): 512.(封面文章)(IF:14.028,引用214次)
- J. Y. Liao, J. Wu, Y. J. Wang, J. H. He, W. X. Deng, K. Hu, Y. C. Zhang, Y. Zhang, H. Yan, D. L. Wang, Q. Liu, M. S. Zeng, H. Phillip Koeffler, E. Song and D. Yin (2017). "Deep sequencing reveals a global reprogramming of lncRNA transcriptome during EMT." Biochim Biophys Acta 1864(10): 1703-1713. (IF:4.739)
- Wang YJ, Yang B, Lai Q, Shi JF, Peng JY, Zhang Y, Hu KS, LiYQ, Peng JW, Yang ZZ, Li YT, Pan Y, Koeffler HP, J. Y. Liao# (共同通讯), Yin D: Reprogramming of m(6)A epitranscriptome iscrucial for shaping of transcriptome and proteome in response to hypoxia. RNA Biol 2020:1-13.(IF:5.35)
- J. Y. Liao, L. M. Ma, Y. H. Guo, Y. C. Zhang, H. Zhou, P. Shao, Y. Q. Chen and L. H. Qu (2010). "Deep sequencing of human nuclear and cytoplasmic small RNAs reveals an unexpectedly complex subcellular distribution of miRNAs and tRNA 3' trailers." PLoS One 5(5): e10563. (IF:2.776,引用222次)
- Li, Y. T., N. Zhou, W. X. Deng, X. Z. Zeng, X. J. Wang, J. W. Peng, B. Yang, Y. J. Wang, J. Y. Liao# (共同通讯)and D. Yin# (2019). "CIRDES: an efficient genome-wide method for in vivo RNA-RNA interactome analysis."Analyst. (封面文章)(IF:4.019)
- Shao, P., J. Y. Liao(共同第一), D. G. Guan, J. H. Yang, L. L. Zheng, Q. Jing, H. Zhou and L. H. Qu (2012). "Drastic expression change of transposon-derived piRNA-like RNAs and microRNAs in early stages of chicken embryos implies a role in gastrulation." RNA Biol 9(2): 212-227. (封面文章)(IF:5.477)
- Zhao Q, Liu J, Deng H, Ma R, Liao JY, Liang H, Hu J, Li J,Guo Z, Cai J, Xu X, Gao Z, Su S: Targeting Mitochondria-Located circRNA SCAR Alleviates NASH via Reducing mROS Output.Cell 2020, 183:76-93 e22.(IF:36.216)
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执业点中山大学孙逸仙纪念医院(三级甲等)基础与转化医学研究中心