个人简介 ——
医学博士，副主任医师，副教授，硕士生导师。美国UCSD大学，Moors癌症研究中心访问学者。现任中国抗癌协会国际医疗交流分会委员，中国老年学和老年医学学会肿瘤康复分会委员，中国老年学和老年医学学会精准医疗分会委员，江苏省研究型医师协会肺结节与MDT专委会委员，江苏省肿瘤康复医学会委员，江苏省老年学学会肿瘤康复专业委会委员，江苏省CRDS-NET学会委员，江苏省医学会疼痛学分会青委、江苏省抗癌协会营养学分会青委。熟练掌握肺癌、乳腺癌、消化道肿瘤等常见肿瘤的诊治，尤其擅长肺癌的综合诊治。作为PI及Sub-PI参与国内外及研究者发起的临床研究项目10余项。主持课题5项，在国内外期刊发表论文40余篇，其中通讯/第一作者SCI论文20余篇。获实用新型专利5项，参编专著1部。获得江苏省卫健委新技术引进奖二等奖。
科研方向 ——
肺癌，乳腺癌，EMT, 能量代谢，免疫逃逸。
发表文章 ——
近五年代表文章：1. Shi Y, Jiang Y, Pan B, Wang Z, Li H, Ma Y, Liu Y, He K, Wang Z, Lu J, Shi M, Shen B, Zhou G, Yin R, Rossi A, Ito K, Santarpia M, Um SW, Wang X, Chen C, Feng J. An exploration of the clinical progression models of osimertinib in the treatment of advanced EGFR-mutant non-small cell lung cancer. Transl Lung Cancer Res. 2022;11(5):817-831.
2. He K, Si L, Pan X, Sun L, Wang Y, Lu J, Wang X. Preoperative Systemic Immune-Inflammation Index (SII) as a Superior Predictor of Long-Term Survival Outcome in Patients With Stage I-II Gastric Cancer After Radical Surgery. Front Oncol. 2022 28;12:829689.
3. He K, Chen C, Xia L, Si L, Pan X, Sun Z, Wang Y, Jiang Y, Shi Y, Zhou B, Wang S, Han J, Shen B, Zhou G, Lu J, Wang X. Deep muscularis propria tumor invasion without lymph node metastasis as a unique subclassification of stage IB gastric cancer: a retrospective study. BMC Gastroenterol. 2022，21;22(1):30.
4. Jiang Y, Shi Y, Liu Y, Wang Z, Ma Y, Shi X, Lu L, Wang Z, Li H, Zhang Y, Liu C, Zhang S, Zhong Z, Lu J, Shi M, Shen B, Zhou G, Yin R, Galetta D, Grenda A, Romero A, Hughes BGM, Chen C, Wang X, Feng J. Efficacy and safety of alectinib in ALK-positive non-small cell lung cancer and blood markers for prognosis and efficacy: a retrospective cohort study. Transl Lung Cancer Res. 2022;11(12):2521-2538.
5. Yingying Jiang，Yue Shi，Zihan Wang，Hang Li，Zhitong Wang，Kang He，Yuxin Ma， Jingiing Xue，Yumeng Shi，Jianwei Lu，Meiqi Shi, Bo Shen, Guoren Zhou, Xiaohua Wang, Cheng Chen, Jifeng Feng. Analysis of adverse drug reactions of Osimertinib in the2nd-line treatment of EGFR mutant advanced nonsmall cell lung cancer. Precision Medical Sciences, 2022,1(1-13):
6. Shi, Y., Ji, M., Jiang, Y., Yin, R., Wang, Z., Li, H., Wang, S., He, K., Ma, Y., Wang, Z., Lu, J., Shi, M., Shen, B., Zhou, G., Leong, T. L., Wang, X., Chen, C., & Feng, J. A cohort study of the efficacy and safety of immune checkpoint inhibitors plus anlotinib versus immune checkpoint inhibitors alone as the treatment of advanced non-small cell lung cancer in the real world. Transl Lung Cancer Res. 2022;11(6):1051-1068.
7. Ye JH, Wang XH, Shi JJ, Yin X, Chen C, Chen Y, Wu HY, Jiong S, Sun Q, Zhang M, Shi XB, Zhou GR, Hassan S, Feng JF, Xu XY, Zhang WJ. Tumor-associated macrophages are associated with response to neoadjuvant chemotherapy and poor outcomes in patients with triple-negative breast cancer. J Cancer. 2021 Mar 15;12(10):2886-2892.
8. Ji Min, Shi Yue, Zou Renrui et al. Prolonged survival in advanced squamous cell lung carcinoma by rational and standardized treatment: A case report of long‐term survival in a patient with NSCLC[J]. Precision Medical Sciences,2021,10(1): （Co-Corresponding author）
9. Wang, X., Xu, G., Zhang, J. et al. The clinical and prognostic significance of paraoxonase-2 in gastric cancer patients: immunohistochemical analysis. Human Cell 32, 487–494 (2019).
10. Wang X , Chen C , Zhou G , et al. Sepia Ink Oligopeptide Induces Apoptosis of Lung Cancer Cells via Mitochondrial Pathway[J]. Cellular Physiology & Biochemistry, 2018:2095-2106.
11. Wang Xiaohua#, Xu Hongxia#, Deng Rong, et al. SMAR1 promotes immune escape of Tri-negative Breast Cancer through a mechanism involving T-bet/PD-1 Axis. Cellular and Molecular Biology，2018；64（12）71-75.
12. Jing Zhou#, Xiao-Hua Wang#, Yi-Xin Zhao,etc. Cancer-Associated Fibroblasts Correlate with Tumor-Associated Macrophages Infiltration and Lymphatic Metastasis in Triple Negative Breast Cancer Patients. (Journal of Cancer. 2018; 9(24): 4635-4641. Co-author)
13. Cheng C#, Xiaohua W#, Ning J, Dan Z, Chengyun Y, Lijun Z, Li Y, Shengfu H, Hong J, He X. MiR-122 exerts anti-proliferative and apoptotic effects on nasopharyngeal carcinoma cells via the PI3K/AKT signaling pathway. Cellular and Molecular Biology, 2018; 64（13）:21-25（Co-author）
14. Wei-jie Zhang#, Xiao-hua Wang#, Shao-ting Gao，Cheng Chen, Xin-yun Xu, Qi sun, Zhi-hua Zhou, Guo-zhong Wu, Qiao Yu*, Guifang Xu*, Yong-Zhong Yao*, Wen-xian Guan*. Tumor-Associated Macrophages Correlates with Phenomenon of EMT and Contributes to Poor Prognosis in Triple-negative Breast Cancer Patients. （Journal of surgical research，2018:222 93-101, Co-author）
15. Cheng Chen, Yuan Wang, Jingfeng Mei， Shoushan Li, Hongxia Xu, Huaping Xiong, Xiaohua Wang*, Xia. He*. Targeting RAD50 increases sensitivity to radiotherapy in colorectal cancer cells. （ Neoplasm, 2018;65(1):75-80, Co-Corresponding author）
16. Shoushan Li,# Ting Yan,# Rong Deng,# Xuesong Jiang, Huaping Xiong, Yuan Wang, Qiao Yu, Xiaohua Wang*, Cheng Chen, and Yichao Zhu*. Low dose of kaempferol suppresses the migration of triple-negative breast cancer cells by downregulating the activities of RhoA and Rac1. （OncoTargets and Therapy， 2017:10 1–11. Corresponding author）
17. Fangfang Jin#, Yanbo Wang#, Yanan Zhu#, Shan Li, Ying Liu, Cheng Chen, Xiaohua Wang*, Ke Zen*，Limin Li*. The miR-125a/HK2 axis regulates cancer cell energy metabolism reprogramming in hepatocellular carcinoma. (Scientific Reports, 2017:8;7(1):3089, Co-Corresponding author）
学术职务 ——
中国抗癌协会国际医疗交流分会委员，中国老年学和老年医学学会肿瘤康复分会委员，中国老年学和老年医学学会精准医疗分会委员，江苏省研究型医师协会肺结节与MDT专委会委员，江苏省肿瘤康复医学会委员，江苏省老年学学会肿瘤康复专业委会委员，江苏省CRDS-NET学会委员，江苏省医学会疼痛学分会青委、江苏省抗癌协会营养学分会青委。

获得课题 ——
目前主持课题5项。

获得荣誉 ——
江苏省卫健委新技术引进奖二等奖。